Grants Awarded

2025 Delphi Consensus study on Clinical Management of WAS has been launched

We are delighted to share the launch of the Delphi Consensus on the Clinical Management of Wiskott-Aldrich Syndrome* — a historic, first-of-its-kind global effort to create clear, expert-driven guidelines for the care of individuals living with WAS.

For too long, families and doctors have had to make difficult decisions without clear guidance — especially for those with milder forms of WAS, symptomatic carriers, or mental health needs. With gene therapy potentially on the horizon, this consensus will also provide guidance on its use, helping families plan for the future with confidence.

What this means for our patients and families:

• Updated guidance on classification of WAS

• Updated management of severe and less severe forms of WAS

• Recommendations on when and for whom HSCT (transplant) or gene therapy may be appropriate

• Best practices for non-transplanted patients

• Guidance on mental health and psychosocial support for patients and families

• Management guidance for female carriers of WAS

With methodological support from Springer, the Wiskott-Aldrich Foundation is spearheading this effort, bringing together WAS experts, mental health experts, patient advocates, and methodologists to work together to make this possible.

• 8 global Key Opinion Leaders forming the Scientific Advisory Committee

• 59 WAS experts from around the world

• 15 mental health professionals

• In collaboration with the Israeli WAS Association

• Methodological support by Springer Health

This initiative brings together the voices of clinicians, patients, caregivers, and advocates — building a truly global standard of care that will improve the lives of patients and families living with WAS everywhere.

When will this be made available? We anticipate publication in Spring of 2026 when all three rounds of Delphi voting will be completed.

From all of us in the WAS community, a heartfelt THANK YOU to our donors and supporters. Your generosity makes life-changing progress possible.

This project was funded by an unrestricted grant by the Wiskott-Aldrich Foundation.

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